NRGN rabbit monoclonal antibody

Catalog # H00004900-K

Size

Price

Stock

Quantity

Size:100 ug x up to 3
Price: -
Stock:
made to order, 8 months
abnova-minus
abnova-plus

* The price is valid only in USA. Please select country.

Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
  • Specifications

    Product Description

    Rabbit monoclonal antibody raised against a human NRGN peptide using ARM Technology.

    Immunogen

    A synthetic peptide of human NRGN is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.

    Host

    Rabbit

    Library Construction

    Non-fusion antibody library from rabbit spleen (ARM Technology).

    Expression

    Overexpression vector and transfection into 293H cell line.

    Reactivity

    Human

    Purification

    Protein A

    Isotype

    IgG

    Quality Control Testing

    Antibody reactive against human NRGN peptide by ELISA and mammalian transfected lysate by Western Blot.

    Storage Buffer

    In 1x PBS, pH 7.4

    Storage Instruction

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

    Deliverable

    Up to three rabbit IgG clones of 100 ug each will be delivered to customer.

    Note

    1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.

  • Applications

    Western Blot (Transfected lysate)

    ELISA

  • Gene Info — NRGN

    Entrez GeneID

    4900

    GeneBank Accession#

    NRGN

    Gene Name

    NRGN

    Gene Alias

    RC3, hng

    Gene Description

    neurogranin (protein kinase C substrate, RC3)

    Omim ID

    602350

    Gene Ontology

    Hyperlink

    Gene Summary

    Neurogranin (NRGN) is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. The exons 1 and 2 encode the protein and exons 3 and 4 contain untranslated sequences. It is suggested that the NRGN is a direct target for thyroid hormone in human brain, and that control of expression of this gene could underlay many of the consequences of hypothyroidism on mental states during development as well as in adult subjects. [provided by RefSeq

    Other Designations

    calmodulin-binding protein|neurogranin|protein kinase C substrate

  • Interactomes
  • Diseases
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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