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ITGB2 rabbit monoclonal antibody

  • Catalog # : H00003689-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human ITGB2 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human ITGB2 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human ITGB2 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 3689
  • GeneBank Accession#:
  • ITGB2
  • Gene Name:
  • ITGB2
  • Gene Alias:
  • CD18,LAD,LCAMB,LFA-1,MAC-1,MF17,MFI7
  • Gene Description:
  • integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
  • Gene Summary:
  • The product of this gene belongs to the integrin beta chain family of proteins. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. This gene encodes the integrin beta chain beta 2. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq
  • Other Designations:
  • CD18 subunit,OTTHUMP00000115278,OTTHUMP00000115279,OTTHUMP00000115281,OTTHUMP00000115282,beta 2 integrin subunit,cell surface adhesion glycoprotein LFA-1/CR3/P150,959 beta subunit precursor),complement receptor C3 beta-subunit,integrin beta 2,integrin bet
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