IDO1 purified MaxPab mouse polyclonal antibody (B01P)
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Specifications
Product Description
Mouse polyclonal antibody raised against a full-length human IDO1 protein.
Immunogen
IDO1 (AAH27882.1, 1 a.a. ~ 403 a.a) full-length human protein.
Sequence
MAHAMENSWTISKEYHIDEEVGFALPNPQENLPDFYNDWMFIAKHLPDLIESGQLRERVEKLNMLSIDHLTDHKSQRLARLVLGCITMAYVWGKGHGDVRKVLPRNIAVPYCQLSKKLELPPILVYADCVLANWKKKDPNKPLTYENMDVLFSFRDGDCSKGFFLVSLLVEIAAASAIKVIPTVFKAMQMQERDTLLKALLEIASCLEKALQVFHQIHDHVNPKAFFSVLRIYLSGWKGNPQLSDGLVYEGFWEDPKEFAGGSAGQSSVFQCFDVLLGIQQTAGGGHAAQFLQDMRRYMPPAHRNFLCSLESNPSVREFVLSKGDAGLREAYDACVKALVSLRSYHLQIVTKYILIPASQQPKENKTSEDPSKLEAKGTGGTDLMNFLKTVRSTTEKSLLKEG
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of IDO1 expression in transfected 293T cell line (H00003620-T01) by IDO1 MaxPab polyclonal antibody.
Lane 1: IDO1 transfected lysate(44.33 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — IDO1
Entrez GeneID
3620GeneBank Accession#
NM_002164.3Protein Accession#
AAH27882.1Gene Name
IDO1
Gene Alias
CD107B, IDO, INDO
Gene Description
indoleamine 2,3-dioxygenase 1
Omim ID
147435Gene Ontology
HyperlinkGene Summary
Gamma-interferon (IFNG; MIM 147570) has an antiproliferative effect on many tumor cells and inhibits intracellular pathogens such as Toxoplasma and Chlamydia, at least partly because of the induction of indoleamine 2,3-dioxygenase (INDO; EC 1.13.11.52). This enzyme catalyzes the degradation of the essential amino acid L-tryptophan to N-formyl-kynurenine.[supplied by OMIM
Other Designations
indole 2,3-dioxygenase|indoleamine-pyrrole 2,3 dioxygenase
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Interactomes
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Pathways
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Diseases
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Publication Reference
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p38 predicts depression and poor outcome in esophageal cancer.
Cheng Y, Qiao Z, Dang C, Zhou B, Li S, Zhang W, Jiang J, Song Y, Zhang J, Diao D.
Oncology Letters 2017 Dec; 4(6):7241.
Application:WB-Ce, Human, Eca‑109, TE‑1 cells.
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p38 predicts depression and poor outcome in esophageal cancer.
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