IDO1 recombinant monoclonal antibody, clone R03-5D4
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human IDO1.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to human IDO1.
Theoretical MW (kDa)
Calculated MW: 45 kD
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunofluorescence(1:50-1:200)
Immunohistochemistry (1:50-1:100)
Immunoprecipitation(1:20)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM Tris-Glycine, pH 7.4 (0.15 M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at -20 °C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Lane 1: human placenta and Lane 2: SKOV-3 lysates with IDO1 recombinant monoclonal antibody, clone R03-5D4 (Cat # RAB02173).Immunohistochemistry
Immunofluorescence
Immunoprecipitation
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Gene Info — IDO1
Entrez GeneID
3620Protein Accession#
P14902Gene Name
IDO1
Gene Alias
CD107B, IDO, INDO
Gene Description
indoleamine 2,3-dioxygenase 1
Omim ID
147435Gene Ontology
HyperlinkGene Summary
Gamma-interferon (IFNG; MIM 147570) has an antiproliferative effect on many tumor cells and inhibits intracellular pathogens such as Toxoplasma and Chlamydia, at least partly because of the induction of indoleamine 2,3-dioxygenase (INDO; EC 1.13.11.52). This enzyme catalyzes the degradation of the essential amino acid L-tryptophan to N-formyl-kynurenine.[supplied by OMIM
Other Designations
indole 2,3-dioxygenase|indoleamine-pyrrole 2,3 dioxygenase
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