GNAQ purified MaxPab mouse polyclonal antibody (B01P)
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Specifications
Product Description
Mouse polyclonal antibody raised against a full-length human GNAQ protein.
Immunogen
GNAQ (AAH57777, 1 a.a. ~ 359 a.a) full-length human protein.
Sequence
MTLESIMACCLSEEAKEARRINDEIERQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDKRGFTKLVYQNIFTAMQAMIRAMDTLKIPYKYEHNKAHAQLVREVDVEKVSAFENPYVDAIKSLWNDPGIQECYDRRREYQLSDSTKYYLNDLDRVADPAYLPTQQDVLRVRVPTTGIIEYPFDLQSVIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIMYSHLVDYFPEYDGPQRDAQAAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNLV
Host
Mouse
Reactivity
Human, Rat
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
GNAQ MaxPab polyclonal antibody. Western Blot analysis of GNAQ expression in rat brain.Western Blot (Transfected lysate)
Western Blot analysis of GNAQ expression in transfected 293T cell line (H00002776-T01) by GNAQ MaxPab polyclonal antibody.
Lane 1: GNAQ transfected lysate(39.6 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — GNAQ
Entrez GeneID
2776GeneBank Accession#
BC057777Protein Accession#
AAH57777Gene Name
GNAQ
Gene Alias
G-ALPHA-q, GAQ
Gene Description
guanine nucleotide binding protein (G protein), q polypeptide
Omim ID
600998Gene Ontology
HyperlinkGene Summary
Guanine nucleotide-binding proteins are a family of heterotrimeric proteins that couple cell surface, 7-transmembrane domain receptors to intracellular signaling pathways. Receptor activation catalyzes the exchange of GTP for GDP bound to the inactive G protein alpha subunit resulting in a conformational change and dissociation of the complex. The G protein alpha and beta-gamma subunits are capable of regulating various cellular effectors. Activation is terminated by a GTPase intrinsic to the G-alpha subunit. G-alpha-q is the alpha subunit of one of the heterotrimeric GTP-binding proteins that mediates stimulation of phospholipase C-beta (MIM 600230).[supplied by OMIM
Other Designations
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