GCG purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
- More Functions
Western Blot (Tissue lysate)
GCG MaxPab rabbit polyclonal antibody. Western Blot analysis of GCG expression in rat brain.
Western Blot (Transfected lysate)
Western Blot analysis of GCG expression in transfected 293T cell line (H00002641-T01) by GCG MaxPab polyclonal antibody.
Lane 1: GCG transfected lysate(20.90 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human GCG protein.
Immunogen
GCG (NP_002045.1, 1 a.a. ~ 180 a.a) full-length human protein.
Sequence
MKSIYFVAGLFVMLVQGSWQRSLQDTEEKSRSFSASQADPLSDPDQMNEDKRHSQGTFTSDYSKYLDSRRAQDFVQWLMNTKRNRNNIAKRHDEFERHAEGTFTSDVSSYLEGQAAKEFIAWLVKGRGRRDFPEEVAIVEELGRRHADGSFSDEMNTILDNLAARDFINWLIQTKITDRK
Host
Rabbit
Reactivity
Human, Rat
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
GCG MaxPab rabbit polyclonal antibody. Western Blot analysis of GCG expression in rat brain.Western Blot (Transfected lysate)
Western Blot analysis of GCG expression in transfected 293T cell line (H00002641-T01) by GCG MaxPab polyclonal antibody.
Lane 1: GCG transfected lysate(20.90 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — GCG
Entrez GeneID
2641GeneBank Accession#
NM_002054Protein Accession#
NP_002045.1Gene Name
GCG
Gene Alias
GLP1, GLP2, GRPP
Gene Description
glucagon
Omim ID
138030Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon. [provided by RefSeq
Other Designations
glicentin-related polypeptide|glucagon-like peptide 1|glucagon-like peptide 2
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Interactome
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Pathway
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Disease
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