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Last updated: 2016/10/23
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DNASE1 purified MaxPab mouse polyclonal antibody (B01P)MaxPab

  • Catalog # : H00001773-B01P
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  • Specification
  • Product Description:
  • Mouse polyclonal antibody raised against a full-length human DNASE1 protein.
  • Immunogen:
  • DNASE1 (NP_005214, 1 a.a. ~ 282 a.a) full-length human protein.
  • Sequence:
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody reactive against mammalian transfected lysate.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of DNASE1 expression in transfected 293T cell line (H00001773-T01) by DNASE1 MaxPab polyclonal antibody.

    Lane 1: DNASE1 transfected lysate(31.02 KDa).
    Lane 2: Non-transfected lysate.
  • PDF DownloadProtocol Download
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 1773
  • Gene Name:
  • DNASE1
  • Gene Alias:
  • DKFZp686H0155,DNL1,DRNI,FLJ38093,FLJ44902
  • Gene Description:
  • deoxyribonuclease I
  • Gene Summary:
  • This gene encodes a member of the DNase family. This protein is stored in the zymogen granules of the nuclear envelope and functions by cleaving DNA in an endonucleolytic manner. At least six autosomal codominant alleles have been characterized, DNASE1*1 through DNASE1*6, and the sequence of DNASE1*2 represented in this record. Mutations in this gene have been associated with systemic lupus erythematosus (SLE), an autoimmune disease. A recombinant form of this protein is used to treat the one of the symptoms of cystic fibrosis by hydrolyzing the extracellular DNA in sputum and reducing its viscosity. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq
  • Other Designations:
  • DNase I, lysosomal,Dornase alfa,human urine deoxyribonuclease I
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