DNASE1 mouse monoclonal antibody (hybridoma)

Catalog # H00001773-M

Size

Price

Stock

Quantity

Size:Up to 5 Clones
Price: USD $ 3,600.00
Stock:
order now, ship in 3 months
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
  • Specification

    Product Description

    Mouse monoclonal antibody raised against a full-length recombinant DNASE1.

    Immunogen

    DNASE1 (NP_005214.2, 1 a.a. ~ 282 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

    Sequence

    MRGMKLLGALLALAALLQGAVSLKIAAFNIQTFGETKMSNATLVSYIVQILSRYDIALVQEVRDSHLTAVGKLLDNLNQDAPDTYHYVVSEPLGRNSYKERYLFVYRPDQVSAVDSYYYDDGCEPCGNDTFNREPAIVRFFSRFTEVREFAIVPLHAAPGDAVAEIDALYDVYLDVQEKWGLEDVMLMGDFNAGCSYVRPSQWSSIRLWTSPTFQWLIPDSADTTATPTHCAYDRIVVAGMLLRGAVVPDSALPFNFQAAYGLSDQLAQAISDHYPVEVMLK

    Host

    Mouse

    Reactivity

    Human

    Quality Control Testing

    Antibody reactivity and specificity confirmed by ELISA and Western Blot.

    Deliverables

    Up to 5 positive hybridoma clones will be delivered to customer in the cryotube format.

    Note

    Customer should check the viability of the hybridomas within one month from the date of receipt. Fee-for-service of long term hybridoma storage can be performed upon customer's request.

  • Applications

    Western Blot (Transfected lysate)

    Western Blot (Recombinant protein)

    ELISA

  • Gene Info — DNASE1

    Entrez GeneID

    1773

    GeneBank Accession#

    NM_005223.3

    Protein Accession#

    NP_005214.2

    Gene Name

    DNASE1

    Gene Alias

    DKFZp686H0155, DNL1, DRNI, FLJ38093, FLJ44902

    Gene Description

    deoxyribonuclease I

    Omim ID

    125505 152700

    Gene Ontology

    Hyperlink

    Gene Summary

    This gene encodes a member of the DNase family. This protein is stored in the zymogen granules of the nuclear envelope and functions by cleaving DNA in an endonucleolytic manner. At least six autosomal codominant alleles have been characterized, DNASE1*1 through DNASE1*6, and the sequence of DNASE1*2 represented in this record. Mutations in this gene have been associated with systemic lupus erythematosus (SLE), an autoimmune disease. A recombinant form of this protein is used to treat the one of the symptoms of cystic fibrosis by hydrolyzing the extracellular DNA in sputum and reducing its viscosity. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq

    Other Designations

    DNase I, lysosomal|Dornase alfa|human urine deoxyribonuclease I

  • Interactome
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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