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Last updated: 2017/7/16

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DDB1 rabbit monoclonal antibody

  • Catalog # : H00001642-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human DDB1 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human DDB1 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human DDB1 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 1642
  • GeneBank Accession#:
  • DDB1
  • Gene Name:
  • DDB1
  • Gene Alias:
  • DDBA,UV-DDB1,XAP1,XPCE,XPE,XPE-BF
  • Gene Description:
  • damage-specific DNA binding protein 1, 127kDa
  • Gene Summary:
  • This gene encodes the large subunit of DNA damage-binding protein which is a heterodimer composed of a large and a small subunit. This protein functions in nucleotide-excision repair. Its defective activity causes the repair defect in the patients with xeroderma pigmentosum complementation group E (XPE). However, it remains for mutation analysis to demonstrate whether the defect in XPE patients is in this gene or the gene encoding the small subunit. In addition, Best vitelliform mascular dystrophy is mapped to the same region as this gene on 11q, but no sequence alternations of this gene are demonstrated in Best disease patients. [provided by RefSeq
  • Other Designations:
  • DDB p127 subunit,damage-specific DNA binding protein 1,damage-specific DNA binding protein 1 (127kD)
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