DDB1 recombinant monoclonal antibody, clone R07-2A3
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More Files
- More Functions
Western Blot
Western blot analysis of DDB1 in Hela, MCF-7, HepG2, U2OS, U251, HL-60 lysates using DDB1 antibody.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry analysis of paraffin-embedded Human lung cancer using DDB1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human DDB1.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to human DDB1.
Theoretical MW (kDa)
Calculated MW: 127 k
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunocytochemistry
Immunofluorescence
Immunohistochemistry (Frozen sections)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoprecipitation
Western Blot
The optimal working dilution should be determined by the end user.Storage Buffer
In 50mM Tris-Glycine, pH 7.4, (0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at 4°C. For longer storage, aliquot and store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of DDB1 in Hela, MCF-7, HepG2, U2OS, U251, HL-60 lysates using DDB1 antibody.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry analysis of paraffin-embedded Human lung cancer using DDB1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.Immunohistochemistry (Frozen sections)
Immunocytochemistry
Immunofluorescence
Immunoprecipitation
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Gene Info — DDB1
Entrez GeneID
1642Protein Accession#
Q16531Gene Name
DDB1
Gene Alias
DDBA, UV-DDB1, XAP1, XPCE, XPE, XPE-BF
Gene Description
damage-specific DNA binding protein 1, 127kDa
Omim ID
600045Gene Ontology
HyperlinkGene Summary
This gene encodes the large subunit of DNA damage-binding protein which is a heterodimer composed of a large and a small subunit. This protein functions in nucleotide-excision repair. Its defective activity causes the repair defect in the patients with xeroderma pigmentosum complementation group E (XPE). However, it remains for mutation analysis to demonstrate whether the defect in XPE patients is in this gene or the gene encoding the small subunit. In addition, Best vitelliform mascular dystrophy is mapped to the same region as this gene on 11q, but no sequence alternations of this gene are demonstrated in Best disease patients. [provided by RefSeq
Other Designations
DDB p127 subunit|damage-specific DNA binding protein 1|damage-specific DNA binding protein 1 (127kD)
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Interactome
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Pathway
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