DDB1 monoclonal antibody, clone AFAH-4
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More Files
- More Functions
Western Blot
Western Blot analysis of DDB1.
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic protein of human DDB1.
Immunogen
A synthetic peptide corresponding to human DDB1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunoprecipitation (1:50)
Immunocytochemistry (1:50-200)
Immunofluorescence (1:50-200)
Western Blot (1:1000-5000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western Blot analysis of DDB1.Immunocytochemistry
Immunofluorescence
Immunoprecipitation
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Gene Info — DDB1
Entrez GeneID
1642Protein Accession#
Q16531Gene Name
DDB1
Gene Alias
DDBA, UV-DDB1, XAP1, XPCE, XPE, XPE-BF
Gene Description
damage-specific DNA binding protein 1, 127kDa
Omim ID
600045Gene Ontology
HyperlinkGene Summary
This gene encodes the large subunit of DNA damage-binding protein which is a heterodimer composed of a large and a small subunit. This protein functions in nucleotide-excision repair. Its defective activity causes the repair defect in the patients with xeroderma pigmentosum complementation group E (XPE). However, it remains for mutation analysis to demonstrate whether the defect in XPE patients is in this gene or the gene encoding the small subunit. In addition, Best vitelliform mascular dystrophy is mapped to the same region as this gene on 11q, but no sequence alternations of this gene are demonstrated in Best disease patients. [provided by RefSeq
Other Designations
DDB p127 subunit|damage-specific DNA binding protein 1|damage-specific DNA binding protein 1 (127kD)
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Interactome
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Pathway
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