CSTB monoclonal antibody (M02A), clone S3

Catalog # H00001476-M02A

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Size:200 uL
Price: USD $ 335.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
Images
Western Blot (Cell lysate)
Application

Western Blot (Cell lysate)

CSTB monoclonal antibody (M02A), clone M2-F1 Western Blot analysis of CSTB expression in A-431 ( Cat # L015V1 ).

QC Test

Western Blot detection against Immunogen (36.52 KDa) .

  • Specification

    Product Description

    Mouse monoclonal antibody raised against a full-length recombinant CSTB.

    Immunogen

    CSTB (AAH03370.1, 1 a.a. ~ 98 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

    Sequence

    MMCGAPSATQPATAETQHIADQVRSQLEEKENKKFPVFKAVSFKSQVVAGTNYFIKVHVGDEDFVHLRVFQSLPHENKPLTLSNYQTNKAKHDELTYF

    Host

    Mouse

    Reactivity

    Human

    Isotype

    IgG1 Kappa

    Quality Control Testing

    Antibody Reactive Against Recombinant Protein.

    Western Blot detection against Immunogen (36.52 KDa) .

    Storage Buffer

    In ascites fluid

    Storage Instruction

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

  • Applications

    Western Blot (Cell lysate)

    CSTB monoclonal antibody (M02A), clone M2-F1 Western Blot analysis of CSTB expression in A-431 ( Cat # L015V1 ).

    Western Blot (Recombinant protein)

    ELISA

  • Gene Info — CSTB

    Entrez GeneID

    1476

    GeneBank Accession#

    BC003370.1

    Protein Accession#

    AAH03370.1

    Gene Name

    CSTB

    Gene Alias

    CST6, EPM1, PME, STFB

    Gene Description

    cystatin B (stefin B)

    Omim ID

    254800 601145

    Gene Ontology

    Hyperlink

    Gene Summary

    The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1). [provided by RefSeq

    Other Designations

    CPI-B|cystatin B|liver thiol proteinase inhibitor|stefin B

  • Interactome
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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