LPHN1 purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of LPHN1 expression in transfected 293T cell line (H00022859-T04) by LPHN1 MaxPab polyclonal antibody.
Lane 1: LPHN1 transfected lysate(20.80 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human LPHN1 protein.
Immunogen
LPHN1 (AAH19928.1, 1 a.a. ~ 201 a.a) full-length human protein.
Sequence
MGLISHLERLMAEGKWGGTGVVEGMGMAEEGAGNGKAVWGMGRGKGERSPSLSSTFPQGRRSQVPGLGSGHPCSGRLDPKSQTPEAPGSGCVLSTCPGPLLSSLSGQPPQPPSLNSRGSIAPGHPSPAPALPFPQRWPLHLCSDLSPSLCPSFSHKCHEFSNIFGSQPAAAMNFVGLRGRGSRKELGGRGQVGGWRDPFCC
Host
Rabbit
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of LPHN1 expression in transfected 293T cell line (H00022859-T04) by LPHN1 MaxPab polyclonal antibody.
Lane 1: LPHN1 transfected lysate(20.80 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — LPHN1
Entrez GeneID
22859GeneBank Accession#
BC019928Protein Accession#
AAH19928.1Gene Name
LPHN1
Gene Alias
CIRL1, CL1, LEC2
Gene Description
latrophilin 1
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. Latrophilin-1 has been shown to recruit the neurotoxin from black widow spider venom, alpha-latrotoxin, to the synapse plasma membrane. Alternative splicing results in multiple variants encoding distinct isoforms
Other Designations
calcium-independent alpha-latrotoxin receptor 1|lectomedin-2
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