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LPHN1 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00022859-T04
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-LPHN1 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 20.8
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-LPHN1 antibody (H00022859-D01P) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00022859-T04
    LPHN1 transfected lysate.
    Western Blot
    QC Testing of H00022859-T04
    Lane 1: LPHN1 transfected lysate ( 20.8 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Gene Name:
  • LPHN1
  • Gene Alias:
  • CIRL1,CL1,LEC2
  • Gene Description:
  • latrophilin 1
  • Gene Summary:
  • This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. Latrophilin-1 has been shown to recruit the neurotoxin from black widow spider venom, alpha-latrotoxin, to the synapse plasma membrane. Alternative splicing results in multiple variants encoding distinct isoforms
  • Other Designations:
  • calcium-independent alpha-latrotoxin receptor 1,lectomedin-2
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