VDR MaxPab mouse polyclonal antibody (B01)
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More Files
- More Functions
Western Blot (Cell lysate)
VDR MaxPab polyclonal antibody. Western Blot analysis of VDR expression in 293.
Western Blot (Transfected lysate)
Western Blot analysis of VDR expression in transfected 293T cell line (H00007421-T01) by VDR MaxPab polyclonal antibody.
Lane 1: VDR transfected lysate(46.97 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to VDR on HeLa cell. [antibody concentration 10 ug/ml]
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human VDR protein.
Immunogen
VDR (NP_000367.1, 1 a.a. ~ 427 a.a) full-length human protein.
Sequence
MEAMAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRRSMKRKALFTCPFNGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMILKRKEEEALKDSLRPKLSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRVNDGGGSHPSRPNSRHTPSFSGDSSSSCSDHCITSSDMMDSSSFSNLDLSEEDSDDPSVTLELSQLSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDDMSWTCGNQDYKYRVSDVTKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGVQDAALIEAIQDRLSNTLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQYRCLSFQPECSMKLTPLVLEVFGNEIS
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Note
For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
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Applications
Western Blot (Cell lysate)
VDR MaxPab polyclonal antibody. Western Blot analysis of VDR expression in 293.Western Blot (Transfected lysate)
Western Blot analysis of VDR expression in transfected 293T cell line (H00007421-T01) by VDR MaxPab polyclonal antibody.
Lane 1: VDR transfected lysate(46.97 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to VDR on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — VDR
Entrez GeneID
7421GeneBank Accession#
NM_000376.2Protein Accession#
NP_000367.1Gene Name
VDR
Gene Alias
NR1I1
Gene Description
vitamin D (1,25- dihydroxyvitamin D3) receptor
Gene Ontology
HyperlinkGene Summary
This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq
Other Designations
vitamin D (1,25-dihydroxyvitamin D3) receptor
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Interactome
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Disease
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