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VDR 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00007421-T01
  • Visit Frequency :
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-VDR full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 47.08
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-VDR antibody (H00007421-B01) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00007421-T01
    VDR transfected lysate.
    Western Blot
    QC Testing of H00007421-T01
    Lane 1: VDR transfected lysate ( 47.08 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 7421
  • Gene Name:
  • VDR
  • Gene Alias:
  • NR1I1
  • Gene Description:
  • vitamin D (1,25- dihydroxyvitamin D3) receptor
  • Gene Summary:
  • This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq
  • Other Designations:
  • vitamin D (1,25-dihydroxyvitamin D3) receptor
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