TNNT2 monoclonal antibody (M02), clone 3H4-F7
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More Files
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Specifications
Product Description
Mouse monoclonal antibody raised against a partial recombinant TNNT2.
Immunogen
TNNT2 (AAH02653, 1 a.a. ~ 268 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MSDIEEVVEEYEEEEQEEAAVEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNMMHFGGYIQKTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDN
Host
Mouse
Reactivity
Human
Isotype
IgG1 kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (55.11 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
TNNT2 monoclonal antibody (M02), clone 3H4-F7 Western Blot analysis of TNNT2 expression in COLO 320 HSR ( Cat # L020V1 ).Western Blot (Recombinant protein)
ELISA
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Gene Info — TNNT2
Entrez GeneID
7139GeneBank Accession#
BC002653Protein Accession#
AAH02653Gene Name
TNNT2
Gene Alias
CMH2, CMPD2, MGC3889, RCM3, TnTC, cTnT
Gene Description
troponin T type 2 (cardiac)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined. [provided by RefSeq
Other Designations
OTTHUMP00000033864|OTTHUMP00000033867|cardiomyopathy, dilated 1D (autosomal dominant)|cardiomyopathy, hypertrophic 2|troponin T type 2, cardiac|troponin T, cardiac muscle|troponin T2, cardiac
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Interactomes
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Pathways
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Diseases
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