Products

Western Blot (Tissue lysate)

INHBB MaxPab rabbit polyclonal antibody. Western Blot analysis of INHBB expression in mouse brain.

Western Blot (Transfected lysate)

Western Blot analysis of INHBB expression in transfected 293T cell line (H00003625-T02) by INHBB MaxPab polyclonal antibody.

Lane 1: INHBB transfected lysate(45.20 KDa).
Lane 2: Non-transfected lysate.

In situ Proximity Ligation Assay (Cell)

Proximity Ligation Analysis of protein-protein interactions between INHBB and ACVR1C. HeLa cells were stained with anti-INHBB rabbit purified polyclonal 1:1200 and anti-ACVR1C mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex, and nuclei were counterstained with DAPI (blue).

Entrez GeneID

3625

GeneBank Accession#

BC030029

Protein Accession#

AAH30029.1

Gene Name

INHBB

Gene Alias

MGC157939

Gene Description

inhibin, beta B

Omim ID

147390

Gene Ontology

Hyperlink

Gene Summary

The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. [provided by RefSeq

Other Designations

Inhibin, beta-2|activin AB beta polypeptide|inhibin beta B subunit