INHBB 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
- More Functions
SDS-PAGE Gel
INHBB transfected lysate.
Western Blot
Lane 1: INHBB transfected lysate ( 45.20 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-INHBB full-length
Host
Human
Theoretical MW (kDa)
45.2
Interspecies Antigen Sequence
Mouse (96); Rat (96)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-INHBB antibody (H00003625-D01P) by Western Blots.
SDS-PAGE Gel
INHBB transfected lysate.
Western Blot
Lane 1: INHBB transfected lysate ( 45.20 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — INHBB
Entrez GeneID
3625GeneBank Accession#
BC030029Protein Accession#
AAH30029.1Gene Name
INHBB
Gene Alias
MGC157939
Gene Description
inhibin, beta B
Omim ID
147390Gene Ontology
HyperlinkGene Summary
The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. [provided by RefSeq
Other Designations
Inhibin, beta-2|activin AB beta polypeptide|inhibin beta B subunit
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Interactome
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Pathway
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Disease
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