ILF3 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Specifications
Product Description
Mouse polyclonal antibody raised against a full-length human ILF3 protein.
Immunogen
ILF3 (NP_004507, 1 a.a. ~ 702 a.a) full-length human protein.
Sequence
MRPMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSEQAESDNMDVPPEDDSKEGAGEQKTEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKPTTALLDKVADNLAIQLAAVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEMEKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRVPTWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEATDAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQIPPSTTYAITPMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKLVSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLALDANKKKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRGFGGANHGGYMNAGAGYGSYGYGGNSATAGYSDFFTDCYGYHDFGSS
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (92)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
ILF3 MaxPab polyclonal antibody. Western Blot analysis of ILF3 expression in human pancreas.Western Blot (Cell lysate)
ILF3 MaxPab polyclonal antibody. Western Blot analysis of ILF3 expression in HeLa.Western Blot (Transfected lysate)
Western Blot analysis of ILF3 expression in transfected 293T cell line (H00003609-T02) by ILF3 MaxPab polyclonal antibody.
Lane 1: ILF3 transfected lysate(77.22 KDa).
Lane 2: Non-transfected lysate.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of purified MaxPab antibody to ILF3 on formalin-fixed paraffin-embedded human small Intestine. [antibody concentration 3 ug/ml]Immunofluorescence
Immunofluorescence of purified MaxPab antibody to ILF3 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — ILF3
Entrez GeneID
3609GeneBank Accession#
NM_004516Protein Accession#
NP_004507Gene Name
ILF3
Gene Alias
CBTF, DRBF, DRBP76, MMP4, MPHOSPH4, MPP4, NF-AT-90, NF110, NF90, NFAR, NFAR-1, NFAR2, TCP110, TCP80
Gene Description
interleukin enhancer binding factor 3, 90kDa
Omim ID
603182Gene Ontology
HyperlinkGene Summary
This gene encodes a double-stranded RNA (dsRNA) binding protein that complexes with other proteins, dsRNAs, small noncoding RNAs, and mRNAs to regulate gene expression and stabilize mRNAs. This protein was first discovered to be a subunit of the nuclear factor of activated T-cells (NFAT); a transcription factor required for T-cell expression of interleukin 2. NFAT is a heterodimer of 45 kDa and 90 kDa proteins, the larger of which is the product of this gene. These proteins have been shown to affect the redistribution of nuclear mRNA to the cytoplasm. Knockdown of NF45 or NF90 protein retards cell growth; possibly by inhibition of mRNA stabilization. In contrast, an isoform (NF110) of this gene that is predominantly restricted to the nucleus has only minor effects on cell growth when its levels are reduced. Alternative splicing results in multiple transcript variants encoding distinct isoforms
Other Designations
M-phase phosphoprotein 4|double-stranded RNA-binding protein, 76 kD|dsRNA binding protein NFAR-2/MPP4|interleukin enhancer binding factor 3|nuclear factor associated with dsRNA|nuclear factor of activated T-cells, 90 kD|translational control protein 80
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Interactomes
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Diseases
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Publication Reference
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Identification and Analysis of Host Proteins that Interact with the 3'-Untranslated Region of Tick-Borne Encephalitis Virus Genomic RNA.
Muto M, Kamitani W, Sakai M, Hirano M, Kobayashi S, Kariwa H, Yoshii K.
Virus Research 2018 Apr; 249:52.
Application:WB, Human, HEK293T cells.
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Identification and Analysis of Host Proteins that Interact with the 3'-Untranslated Region of Tick-Borne Encephalitis Virus Genomic RNA.
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