TBK1 recombinant monoclonal antibody, clone 14D10
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More Files
- More Functions
Immunohistochemistry
Immunohistochemistry image of TBK1 recombinant monoclonal antibody, clone 14D10 diluted at 1:100 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system.
Flow Cytometry
Overlay Peak curve showing A549 cells stained with TBK1 recombinant monoclonal antibody, clone 14D10 (red line) at 1:100.
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human TBK1.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human TBK1.
Reactivity
Human
Form
Liquid
Purification
Affinity chromatography purification
Isotype
IgG
Recommend Usage
ELISA
Flow Cytometry(1:50-1:200)
Immunohistochemistry(1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH7.4 (150 mM NaCl, 0.02% sodium azide and 50% glycerol)
Storage Instruction
Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry
Immunohistochemistry image of TBK1 recombinant monoclonal antibody, clone 14D10 diluted at 1:100 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system.Enzyme-linked Immunoabsorbent Assay
Flow Cytometry
Overlay Peak curve showing A549 cells stained with TBK1 recombinant monoclonal antibody, clone 14D10 (red line) at 1:100. -
Gene Info — TBK1
Entrez GeneID
29110Protein Accession#
Q9UHD2Gene Name
TBK1
Gene Alias
FLJ11330, NAK, T2K
Gene Description
TANK-binding kinase 1
Omim ID
604834Gene Ontology
HyperlinkGene Summary
The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. For example, the protein can form a complex with the IKB protein TANK and TRAF2 and release the NFKB inhibition caused by TANK. [provided by RefSeq
Other Designations
NF-kB-activating kinase
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Interactome
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Pathway
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Disease
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