MAPK10 recombinant monoclonal antibody, clone 29E10
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More Files
- More Functions
Western Blot
Western Blot analysis of Lane 1: PC-3 whole cell lysate; Lane 2: Mouse brain tissue.
Immunohistochemistry
Immunohistochemistry image of MAPK10 recombinant monoclonal antibody, clone 29E10 diluted at 1:100 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system.
Immunofluorescence
Immunofluorescence staining of PC-3 Cells with MAPK10 recombinant monoclonal antibody, clone 29E10 at 1:50, counter-stained with DAPI.
Flow Cytometry
Overlay Peak curve showing PC-3 cells stained with MAPK10 recombinant monoclonal antibody, clone 29E10 (red line) at 1:100.
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human and mouse MAPK10.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human MAPK10.
Reactivity
Human, Mouse
Form
Liquid
Purification
Affinity chromatography purification
Isotype
IgG
Recommend Usage
ELISA
Flow Cytometry(1:50-1:200)
Immunohistochemistry(1:50-1:200)
Immunofluorescence(1:20-1:200)
Western Blot(1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH7.4 (150 mM NaCl, 0.02% sodium azide and 50% glycerol)
Storage Instruction
Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western Blot analysis of Lane 1: PC-3 whole cell lysate; Lane 2: Mouse brain tissue.Immunohistochemistry
Immunohistochemistry image of MAPK10 recombinant monoclonal antibody, clone 29E10 diluted at 1:100 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system.Immunofluorescence
Immunofluorescence staining of PC-3 Cells with MAPK10 recombinant monoclonal antibody, clone 29E10 at 1:50, counter-stained with DAPI.Enzyme-linked Immunoabsorbent Assay
Flow Cytometry
Overlay Peak curve showing PC-3 cells stained with MAPK10 recombinant monoclonal antibody, clone 29E10 (red line) at 1:100. -
Gene Info — MAPK10
Entrez GeneID
5602Protein Accession#
P53779Gene Name
MAPK10
Gene Alias
FLJ12099, FLJ33785, JNK3, JNK3A, MGC50974, PRKM10, p493F12, p54bSAPK
Gene Description
mitogen-activated protein kinase 10
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with, and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4). Cyclin-dependent kianse 5 can phosphorylate, and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq
Other Designations
JNK3 alpha protein kinase|MAP kinase|OTTHUMP00000161180|OTTHUMP00000161182|OTTHUMP00000161183|c-Jun N-terminal kinase 3|c-Jun kinase 3|stress activated protein kinase JNK3|stress activated protein kinase beta
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