NTRK1 recombinant monoclonal antibody, clone 2A5
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More Files
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Western Blot
Western blot analysis of Rat Brain whole cell lysate, Mouse Brain whole cell lysate with NTRK1 recombinant monoclonal antibody, clone 2A5 (Cat # RAB07502).
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human NTRK1.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human NTRK1.
Theoretical MW (kDa)
Calculated MW: 88, 8
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Affinity chromatography purification
Isotype
IgG
Recommend Usage
ELISA
Western Blot (1:500-1:5000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH7.4 (150 mM NaCl, 0.02% sodium azide and 50% glycerol)
Storage Instruction
Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Rat Brain whole cell lysate, Mouse Brain whole cell lysate with NTRK1 recombinant monoclonal antibody, clone 2A5 (Cat # RAB07502).Enzyme-linked Immunoabsorbent Assay
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Gene Info — NTRK1
Entrez GeneID
4914Protein Accession#
P04629Gene Name
NTRK1
Gene Alias
DKFZp781I14186, MTC, TRK, TRK1, TRKA, p140-TrkA
Gene Description
neurotrophic tyrosine kinase, receptor, type 1
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq
Other Designations
OTTHUMP00000038736|Oncogene TRK|high affinity nerve growth factor receptor|tyrosine kinase receptor A
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Interactome
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Pathway
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Disease
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