NTRK1 recombinant monoclonal antibody, clone MNAC13
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More Files
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Immunofluorescence
Immunofluorescence analysis of NTRK1 (green) in HeLa cells using human anti-TrkA recombinant monoclonal antibody, clone MNAC13 (Cat # RAB03916), and DAPI(blue).
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human TrkA ECD.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to human TrkA ECD.
Reactivity
Human
Form
Liquid
Isotype
IgG
Recommend Usage
Blocking
ELISA
Immunofluorescence
Immunohistochemistry
Surface Plasma Resonance
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% Proclin 300)
Storage Instruction
Store at 4°C for 3 months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunofluorescence
Immunofluorescence analysis of NTRK1 (green) in HeLa cells using human anti-TrkA recombinant monoclonal antibody, clone MNAC13 (Cat # RAB03916), and DAPI(blue).Enzyme-linked Immunoabsorbent Assay
Blocking
Surface Plasmon Resonance
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Gene Info — NTRK1
Entrez GeneID
4914Protein Accession#
P04629Gene Name
NTRK1
Gene Alias
DKFZp781I14186, MTC, TRK, TRK1, TRKA, p140-TrkA
Gene Description
neurotrophic tyrosine kinase, receptor, type 1
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq
Other Designations
OTTHUMP00000038736|Oncogene TRK|high affinity nerve growth factor receptor|tyrosine kinase receptor A
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Interactome
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Disease
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