F3 recombinant monoclonal antibody, clone R07-3G5
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More Files
- More Functions
Western Blot
Western blot analysis of Lane 1: A549 whole cell lysate, Lane 2: HL-60 whole cell lysate and Lane 3: U2OS whole cell lysate with F3 recombinant monoclonal antibody, clone R07-3G5 (Cat # RAB04430).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human lung cancer with F3 recombinant monoclonal antibody, clone R07-3G5 (Cat # RAB04430).
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human F3.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to human F3.
Theoretical MW (kDa)
Calculated MW: 33 kD
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:100)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM Tris-Glycine, pH 7.4 (0.15 M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Lane 1: A549 whole cell lysate, Lane 2: HL-60 whole cell lysate and Lane 3: U2OS whole cell lysate with F3 recombinant monoclonal antibody, clone R07-3G5 (Cat # RAB04430).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human lung cancer with F3 recombinant monoclonal antibody, clone R07-3G5 (Cat # RAB04430). -
Gene Info — F3
Entrez GeneID
2152Protein Accession#
P13726Gene Name
F3
Gene Alias
CD142, TF, TFA
Gene Description
coagulation factor III (thromboplastin, tissue factor)
Omim ID
134390Gene Ontology
HyperlinkGene Summary
This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. [provided by RefSeq
Other Designations
OTTHUMP00000012426|coagulation factor III|tissue factor
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Interactome
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Pathway
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Disease
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