RRM2 recombinant monoclonal antibody, clone SAIC-30C-18
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against synthetic peptide corresponding to the KLH-conjugated peptide "IEQEFLTEALPVK" derived from Ribonucleoside-diphosphate reductase subunit M2 (RRM2). RRM2 provides precursors required for DNA synthesis.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to the KLH-conjugated peptide "IEQEFLTEALPVK" derived from Ribonucleoside-diphosphate reductase subunit M2 (RRM2). RRM2 provides precursors required for DNA synthesis.
Sequence
IEQEFLTEALPVK
Reactivity
Human
Form
Liquid
Conjugation
Unconjugated
Concentration
batch dependent
Isotype
IgG
Recommend Usage
ELISA
Flow cytometry
Immunofluorescence
Immuno-MRM
Western Blot
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS with 0.02% Proclin 300
Storage Instruction
Store at 4°C for 3 months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
For research use only.
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Applications
Western Blot
Western blot analysis of Jurkat cell lysate using anti-RRM2 recombinant monoclonal antibody, clone SAIC-30C-18 (Cat # RAB03840).Immunofluorescence
Immunofluorescence analysis of RRM2 (green) in HeLa cells using human anti-RRM2 recombinant monoclonal antibody, clone SAIC-30C-18 (Cat # RAB03840), and DAPI(blue).Enzyme-linked Immunoabsorbent Assay
Flow Cytometry
Flow-cytometry analysis of RRM2 in HeLa cells using human anti-RRM2 recombinant monoclonal antibody, clone SAIC-30C-18 (Cat # RAB03840).Immuno-MRM (multiple reaction monitoring)
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Gene Info — RRM2
Entrez GeneID
6241Protein Accession#
P31350Gene Name
RRM2
Gene Alias
R2, RR2M
Gene Description
ribonucleotide reductase M2 polypeptide
Omim ID
180390Gene Ontology
HyperlinkGene Summary
This gene encodes one of two non-identical subunits for ribonucleotide reductase. This reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the encoded protein (M2) is regulated in a cell-cycle dependent fashion. Transcription from this gene can initiate from alternative promoters, which results in two isoforms that differ in the lengths of their N-termini. Related pseudogenes have been identified on chromosomes 1 and X. [provided by RefSeq
Other Designations
ribonucleotide reductase M2 subunit
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Interactome
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Disease
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