GSK3B recombinant monoclonal antibody
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against GSK3B.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant GSK3B.
Theoretical MW (kDa)
46
Reactivity
Human, Mouse
Specificity
This antibody detects endogenous levels of GSK3B and does not cross-react with related proteins.
Form
Liquid
Purification
Protein A purification
Isotype
IgG
Recommend Usage
Flow Cytometry (1:50-1:100)
Immunocytochemistry (1:50-1:200)
Immunofluorescence (1:50-1:200)
Immunohistochemistry (1:50-1:200)
Western Blot (1:1000-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH7.2 (50% glycerol and 0.02% sodium azide)
Storage Instruction
Store at 4°C short term.
Aliquot and store at -20°C long term.
Avoid freeze-thaw cycles.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of Lane1:Hela whole cell lysate Lane2:293 whole cell lysate Lane3:NIH/3T3 whole cell lysate Lane4:PC12 whole cell lysate with GSK3B recombinant monoclonal antibody (Cat # RAB02742) at 1:1000 dilution.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human breast tissue using GSK3B recombinant monoclonal antibody (Cat # RAB02742). Counter stained with hematoxylin.Immunocytochemistry
Immunocytochemical staining of PC-3M cells using GSK3B recombinant monoclonal antibody (Cat # RAB02742)(green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton *100/PBS.Immunofluorescence
Flow Cytometry
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Gene Info — GSK3B
Entrez GeneID
2932Protein Accession#
P49841Gene Name
GSK3B
Gene Alias
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Gene Description
glycogen synthase kinase 3 beta
Omim ID
605004Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene
Other Designations
GSK3beta isoform|glycogen synthase kinase-3 beta
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Interactome
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Pathway
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Disease
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