APPL1 recombinant monoclonal antibody, clone R05-8D5
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More Files
- More Functions
Western Blot
Western blot analysis of APPL in rat Brain, C6, 3T3, Hela lysates using human APPL recombinant monoclonal antibody, clone R05-8D5 (Cat # RAB01597).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry (Formalin-fixed paraffin-embedded sections) of Human lung cancer with APPL recombinant monoclonal antibody, clone R05-8D5 (Cat # RAB01597).
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against synthetic peptide of human APPL.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human APPL
Theoretical MW (kDa)
Calculated MW: 80 kD
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:100)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM Tris-Glycine, pH 7.4 (0.15 M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of APPL in rat Brain, C6, 3T3, Hela lysates using human APPL recombinant monoclonal antibody, clone R05-8D5 (Cat # RAB01597).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry (Formalin-fixed paraffin-embedded sections) of Human lung cancer with APPL recombinant monoclonal antibody, clone R05-8D5 (Cat # RAB01597). -
Gene Info — APPL1
Entrez GeneID
26060Protein Accession#
Q9UKG1Gene Name
APPL1
Gene Alias
APPL, DIP13alpha
Gene Description
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
Omim ID
604299Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus. [provided by RefSeq
Other Designations
AKT2 interactor|adaptor protein containing pH domain, PTB domain and leucine zipper motif 1|signaling adaptor protein DIP13alpha
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Interactome
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Pathway
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Disease
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