MCL1 recombinant monoclonal antibody, clone R04-3A4
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More Files
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human MCL1.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to human MCL1.
Theoretical MW (kDa)
Calculated MW: 37 kD
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunocytochemistry
Immunofluorescence
Immunoprecipitation
Western Blot
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM Tris-Glycine, pH 7.4 (0.15 M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at 4°C. For longer storage, aliquot and store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of CD147 in rat Brain, C6, 3T3 lysates using CD147 antibody.Western Blot
Western blot analysis of MCL1 in C6 lysates using MCL1 antibody.Immunocytochemistry
Immunocytochemistry analysis of CD147 (green) in 3T3 using CD147 antibody,and DAPI(blue).Immunocytochemistry
Immunofluorescence
Immunofluorescence
Immunoprecipitation
Immunoprecipitation
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Gene Info — MCL1
Entrez GeneID
4170Protein Accession#
Q07820Gene Name
MCL1
Gene Alias
BCL2L3, EAT, MCL1L, MCL1S, MGC104264, MGC1839, TM
Gene Description
myeloid cell leukemia sequence 1 (BCL2-related)
Omim ID
159552Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the Bcl-2 family. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. The longer gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene product (isoform 2) promotes apoptosis and is death-inducing. [provided by RefSeq
Other Designations
OTTHUMP00000032794|OTTHUMP00000032795|induced myeloid leukemia cell differentiation protein Mcl-1|myeloid cell leukemia sequence 1|myeloid cell leukemia sequence 1, isoform 1
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Interactome
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Disease
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