CDX2 polyclonal antibody
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More Files
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Western Blot (Tissue lysate)
CDX2 polyclonal antibody (Cat # PAB6998) (1 ug/mL) staining of human kidney lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of CDX2.
Immunogen
A synthetic peptide corresponding to human CDX2.
Sequence
EQLSPGGQRRNLCE
Host
Goat
Theoretical MW (kDa)
33.5
Reactivity
Human
Specificity
This antibody is not expected to cross-react with CDX1 and 4.
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:4000)
Western Blot (1-3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
CDX2 polyclonal antibody (Cat # PAB6998) (1 ug/mL) staining of human kidney lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — CDX2
Entrez GeneID
1045Protein Accession#
NP_001256.1Gene Name
CDX2
Gene Alias
CDX-3, CDX3
Gene Description
caudal type homeobox 2
Omim ID
600297Gene Ontology
HyperlinkGene Summary
The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear proteins that bind to specific sequences within the promoter of the insulin gene (INS; MIM 176730) and interact with RNA polymerase to activate or repress transcription. The proteins LMX1 (MIM 600298) and CDX3 are homeodomain proteins that bind an A/T-rich sequence in the insulin promoter and stimulate its transcription (German et al., 1994 [PubMed 7698771]).[supplied by OMIM
Other Designations
OTTHUMP00000018176|caudal type homeo box transcription factor 2|caudal type homeobox transcription factor 2
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Interactome
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Disease
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Publication Reference
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Vertebrate endoderm development.
Wells JM, Melton DA.
Annual Review of Cell and Developmental Biology 1999 Jan; 15:393.
Application：IF, IHC, WB-Ce, WB-Ti, Human, Mouse, Mouse embryos.
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Vertebrate endoderm development.
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