MAX polyclonal antibody
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More Files
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Western Blot (Cell lysate)
MAX polyclonal antibody (Cat # PAB6023) staining (0.1 ug/mL) of Jurkat lysate (RIPA buffer, 1.4E+05 cells per lane). Primary incubated for 12 hour. Detected by western blot using chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of MAX.
Immunogen
A synthetic peptide corresponding to human MAX.
Sequence
C-EEPQSRKKLRMEAS
Host
Goat
Theoretical MW (kDa)
18.3, 17.2
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:32000)
Western blot (0.1-0.3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
MAX polyclonal antibody (Cat # PAB6023) staining (0.1 ug/mL) of Jurkat lysate (RIPA buffer, 1.4E+05 cells per lane). Primary incubated for 12 hour. Detected by western blot using chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — MAX
Entrez GeneID
4149Protein Accession#
NP_002373Gene Name
MAX
Gene Alias
MGC10775, MGC11225, MGC18164, MGC34679, MGC36767, bHLHd4, bHLHd5, bHLHd6, bHLHd7, bHLHd8, orf1
Gene Description
MYC associated factor X
Omim ID
154950Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Multiple alternatively spliced transcript variants have been described for this gene but the full-length nature for some of them is unknown. [provided by RefSeq
Other Designations
MAX protein|helix-loop-helix zipper protein|myc-associated factor X
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Interactome
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Pathway
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Publication Reference
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Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc.
Blackwood EM, Eisenman RN.
Science 1991 Mar; 251(4998):1211.
Application：GSA, IP, Synthesized Proteins.
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Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc.
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