MAX polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human appendix with MAX polyclonal antibody (Cat # PAB29412) shows nuclear positivity in lymphoid tissue at 1:50-1:200 dilution.
Immunofluorescence
Immunofluorescent staining of human cell line A-431 with MAX polyclonal antibody (Cat # PAB29412) at 1-4 ug/mL concentration shows positivity in cytoplasm and nucleus but excluded from the nucleoli.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant human MAX.
Immunogen
Recombinant protein corresponding to human MAX.
Sequence
MSDNDDIEVESDEEQPRFQSAADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKASRAQILDKATEYIQYMRRKNHTHQQDIDDLKRQNALLEQQVRALEKARSSAQLQTNYPSSD
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
Immunofluorescence (1-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human appendix with MAX polyclonal antibody (Cat # PAB29412) shows nuclear positivity in lymphoid tissue at 1:50-1:200 dilution.Immunofluorescence
Immunofluorescent staining of human cell line A-431 with MAX polyclonal antibody (Cat # PAB29412) at 1-4 ug/mL concentration shows positivity in cytoplasm and nucleus but excluded from the nucleoli. -
Gene Info — MAX
Entrez GeneID
4149Gene Name
MAX
Gene Alias
MGC10775, MGC11225, MGC18164, MGC34679, MGC36767, bHLHd4, bHLHd5, bHLHd6, bHLHd7, bHLHd8, orf1
Gene Description
MYC associated factor X
Omim ID
154950Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Multiple alternatively spliced transcript variants have been described for this gene but the full-length nature for some of them is unknown. [provided by RefSeq
Other Designations
MAX protein|helix-loop-helix zipper protein|myc-associated factor X
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Interactome
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Pathway
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