LEPR polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human prostate with LEPR polyclonal antibody (Cat # PAB31156) shows strong granular, cytoplasmic positivity in glandular cells.
Immunofluorescence
Immunofluorescent staining of BJ cells with LEPR polyclonal antibody (Cat # PAB31156) (Green) shows no positivity.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human LEPR.
Immunogen
Recombinant protein corresponding to human LEPR.
Sequence
IYFPPKILTSVGSNVSFHCIYKKENKIVPSKEIVWWMNLAEKIPQSQYDVVSDHVSKVTFFNLNETKPRGKFTYDAVYCCNEHECHHRYAEL
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunofluorescence (1-4 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C for short term storage. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human prostate with LEPR polyclonal antibody (Cat # PAB31156) shows strong granular, cytoplasmic positivity in glandular cells.Immunofluorescence
Immunofluorescent staining of BJ cells with LEPR polyclonal antibody (Cat # PAB31156) (Green) shows no positivity. -
Gene Info — LEPR
Entrez GeneID
3953Protein Accession#
P48357Gene Name
LEPR
Gene Alias
CD295, OBR
Gene Description
leptin receptor
Omim ID
601007Gene Ontology
HyperlinkGene Summary
Leptin (LEP; MIM 164160), an adipocyte-specific hormone that regulates adipose-tissue mass through hypothalamic effects on satiety and energy expenditure, acts through the leptin receptor (LEPR), a single-transmembrane-domain receptor of the cytokine receptor family.[supplied by OMIM
Other Designations
OB receptor|OTTHUMP00000010693|OTTHUMP00000010694
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Interactome
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Pathway
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Disease
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