LEPR monoclonal antibody (M05), clone 2H5
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant LEPR.
Immunogen
LEPR (NP_001003679, 31 a.a. ~ 130 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
WRFKLSCMPPNSTYDYFLLPAGLSKNTSNSNGHYETAVEPKFNSSGTHFSNLSKTTFHCCFRSEQDRNCSLCADNIEGKTFVSTVNSLVFQQIDANWNIQ
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (55)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged LEPR is 1 ng/ml as a capture antibody.ELISA
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Gene Info — LEPR
Entrez GeneID
3953GeneBank Accession#
NM_001003679Protein Accession#
NP_001003679Gene Name
LEPR
Gene Alias
CD295, OBR
Gene Description
leptin receptor
Omim ID
601007Gene Ontology
HyperlinkGene Summary
Leptin (LEP; MIM 164160), an adipocyte-specific hormone that regulates adipose-tissue mass through hypothalamic effects on satiety and energy expenditure, acts through the leptin receptor (LEPR), a single-transmembrane-domain receptor of the cytokine receptor family.[supplied by OMIM
Other Designations
OB receptor|OTTHUMP00000010693|OTTHUMP00000010694
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Interactome
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Pathway
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Disease
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