NXF1 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of NXF1 polyclonal antibody (Cat # PAB28507) in K562 cell line lysates (35ug/lane). NXF1 (arrow) was detected using the purified polyclonal antibody.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) of human stomach tissue with NXF1 polyclonal antibody (Cat # PAB28507) followed by peroxidase conjugation of the secondary antibody and DAB staining.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of NXF1.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to amino acids 1-30 at N-terminal region at human NXF1.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Protein A purification
Recommend Usage
Immunohistochemistry (1:10-50)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of NXF1 polyclonal antibody (Cat # PAB28507) in K562 cell line lysates (35ug/lane). NXF1 (arrow) was detected using the purified polyclonal antibody.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) of human stomach tissue with NXF1 polyclonal antibody (Cat # PAB28507) followed by peroxidase conjugation of the secondary antibody and DAB staining. -
Gene Info — NXF1
Entrez GeneID
10482Protein Accession#
Q9UBU9Gene Name
NXF1
Gene Alias
DKFZp667O0311, MEX67, TAP
Gene Description
nuclear RNA export factor 1
Omim ID
602647Gene Ontology
HyperlinkGene Summary
This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA. It is the vertebrate homologue of the yeast protein Mex67p. The encoded protein overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses. Alternative splicing results in multiple transcript variants. [provided by RefSeq
Other Designations
tip associating protein
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Interactome
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