NCBP1 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of NCBP1 in HeLa cell lysate with NCBP1 polyclonal antibody (Cat # PAB27446) at (lane 1) 1 and (lane 2) 2 ug/mL.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of NCBP1.
Immunogen
A synthetic peptide corresponding to 17 amino acids at internal region of human NCBP1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
NCBP1 antibody is human, mouse and rat reactive. At least two isoforms of NCBP1 are known to exist; this antibody will detect both isoforms of NCBP1.
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Isotype
IgG
Recommend Usage
Western Blot (1-2 ug/mL)
Immunocytochemistry (2.5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of NCBP1 in HeLa cell lysate with NCBP1 polyclonal antibody (Cat # PAB27446) at (lane 1) 1 and (lane 2) 2 ug/mL.Immunocytochemistry
Enzyme-linked Immunoabsorbent Assay
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Gene Info — NCBP1
Entrez GeneID
4686Protein Accession#
NP_002477Gene Name
NCBP1
Gene Alias
CBP80, MGC2087, NCBP
Gene Description
nuclear cap binding protein subunit 1, 80kDa
Omim ID
600469Gene Ontology
HyperlinkGene Summary
The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay. [provided by RefSeq
Other Designations
OTTHUMP00000021753
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