NCBP1 monoclonal antibody (M04), clone 1E9
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant NCBP1.
Immunogen
NCBP1 (NP_002477, 2 a.a. ~ 99 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
SRRRHSDENDGGQPHKRRKTSDANETEDHLESLICKVGEKSACSLESNLEGLAGVLEADLPNYKSKILRLLCTVARLLPEKLTIYTTLVGLLNARNYN
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (99); Rat (99)
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.52 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of monoclonal antibody to NCBP1 on formalin-fixed paraffin-embedded human testis. [antibody concentration 3 ug/ml]ELISA
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Gene Info — NCBP1
Entrez GeneID
4686GeneBank Accession#
NM_002486Protein Accession#
NP_002477Gene Name
NCBP1
Gene Alias
CBP80, MGC2087, NCBP
Gene Description
nuclear cap binding protein subunit 1, 80kDa
Omim ID
600469Gene Ontology
HyperlinkGene Summary
The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay. [provided by RefSeq
Other Designations
OTTHUMP00000021753
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