CELSR3 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of CELSR3.
Immunogen
A synthetic peptide corresponding to internal of human CELSR3.
Host
Rabbit
Reactivity
Human
Specificity
This antibody detects endogenous levels of total CELSR3 protein.
Form
Liquid
Recommend Usage
Immunohistochemistry (1:50-1:100)
Immunofluorescence (1:500-1:1000)
ELISA (1:20000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry analysis of paraffin-embedded human brain tissue using CELSR3 polyclonal antibody (Cat # PAB17505).
Peptide "+" means "with peptide blocking".Immunofluorescence
Immunofluorescence analysis of HepG2 cells, using CELSR3 polyclonal antibody (Cat # PAB17505).
Peptide "+" means "with peptide blocking".Enzyme-linked Immunoabsorbent Assay
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Gene Info — CELSR3
Entrez GeneID
1951Protein Accession#
Q9NYQ7Gene Name
CELSR3
Gene Alias
CDHF11, EGFL1, FMI1, HFMI1, MEGF2, RESDA1
Gene Description
cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)
Omim ID
604264Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. The specific function of this particular member has not been determined. [provided by RefSeq
Other Designations
EGF-like-domain, multiple 1|anchor protein|cadherin EGF LAG seven-pass G-type receptor 3|epidermal growth factor-like 1|multiple EGF-like domains 2
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