CELSR3 monoclonal antibody (M01), clone 2F7
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant CELSR3.
Immunogen
CELSR3 (NP_001398, 71 a.a. ~ 180 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
REDGGPGLGVREPIFVGLRGRRQSARNSRGPPEQPNEELGIEHGVQPLGSRERETGQGPGSVLYWRPEVSSCGRTGPLQRGSLSPGALSSGVPGSGNSSPLPSDFLIRHH
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (65); Rat (63)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.84 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged CELSR3 is approximately 0.03ng/ml as a capture antibody.ELISA
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Gene Info — CELSR3
Entrez GeneID
1951GeneBank Accession#
NM_001407Protein Accession#
NP_001398Gene Name
CELSR3
Gene Alias
CDHF11, EGFL1, FMI1, HFMI1, MEGF2, RESDA1
Gene Description
cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)
Omim ID
604264Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. The specific function of this particular member has not been determined. [provided by RefSeq
Other Designations
EGF-like-domain, multiple 1|anchor protein|cadherin EGF LAG seven-pass G-type receptor 3|epidermal growth factor-like 1|multiple EGF-like domains 2
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