SNCG polyclonal antibody
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More Files
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Western Blot
Western blot analysis of recombinant synuclein family (alpha - , beta - and gamma -) and HT - 29 (colon adenocarcinoma) cell extracts were resolved by SDS - PAGE , transferred to PVDF membrane and probed with polyclonal SNCG polyclonal antibody (1 : 1000) (Cat # PAB1627) . Proteins were visualized using a goat anti - rabbit secondary antibody conjugated to HRP and the ECL detection system.
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Specification
Product Description
Rabbit polyclonal antibody raised against full length recombinant SNCG.
Immunogen
Recombinant protein corresponding to full length human SNCG.
Host
Rabbit
Reactivity
Human
Specificity
This antibody is specific to SNCG and does not cross-react with SNCA and SNCB.
Form
Liquid
Purification
Protein A purification
Recommend Usage
ELISA
Western Blot
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (10% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of recombinant synuclein family (alpha - , beta - and gamma -) and HT - 29 (colon adenocarcinoma) cell extracts were resolved by SDS - PAGE , transferred to PVDF membrane and probed with polyclonal SNCG polyclonal antibody (1 : 1000) (Cat # PAB1627) . Proteins were visualized using a goat anti - rabbit secondary antibody conjugated to HRP and the ECL detection system.Enzyme-linked Immunoabsorbent Assay
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Gene Info — SNCG
Entrez GeneID
6623Protein Accession#
NP_003078.2Gene Name
SNCG
Gene Alias
BCSG1, SR
Gene Description
synuclein, gamma (breast cancer-specific protein 1)
Omim ID
602998Gene Ontology
HyperlinkGene Summary
Summary: This gene encodes a member of the synuclein family of proteins which are believed to be involved in the pathogenesis of neurodegenerative diseases. Mutations in this gene have also been associated with breast tumor development. [provided by RefSeq
Other Designations
OTTHUMP00000020013|breast cancer-specific protein 1|persyn|synoretin|synuclein, gamma (breast cancer-specific gene 1)
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Interactome
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Disease
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Publication Reference
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Loss of epigenetic control of synuclein-gamma gene as a molecular indicator of metastasis in a wide range of human cancers.
Liu H, Liu W, Wu Y, Zhou Y, Xue R, Luo C, Wang L, Zhao W, Jiang JD, Liu J.
Cancer Research 2005 Sep; 65(17):7635.
Application：IHC-P, Human, Human cancer tissues.
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The synucleins.
George JM.
Genome Biol 2001 Dec; 3(1):REVIEWS300.
Application：IHC, WB, Bovine, Chicken, Human, Mouse, Rat, Brains, Cancers.
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Identification of a breast cancer-specific gene, BCSG1, by direct differential cDNA sequencing.
Ji H, Liu YE, Jia T, Wang M, Liu J, Xiao G, Joseph BK, Rosen C, Shi YE.
Cancer Research 1997 Feb; 57(4):759.
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Loss of epigenetic control of synuclein-gamma gene as a molecular indicator of metastasis in a wide range of human cancers.
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