TNFRSF11B (Human) Recombinant Protein
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More Files
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Specification
Product Description
Human TNFRSF11B (O00300, 22 a.a. - 401 a.a.) partial-length recombinant protein with His tag at C-Terminus expressed in Baculovirus.
Sequence
ADPETFPPKYLHYDEETSHQLLCDKCPPGTYLKQHCTAKWKTVCAPCPDHYYTDSWHTSDECLYCSPVCKELQYVKQECNRTHNRVCECKEGRYLEIEFCLKHRSCPPGFGVVQAGTPERNTVCKRCPDGFFSNETSSKAPCRKHTNCSVFGLLLTQKGNATHDNICSGNSESTQKCGIDVTLCEEAFFRFAVPTKFTPNWLSVLVDNLPGTKVNAESVERIKRQHSSQEQTFQLLKLWKHQNKDQDIVKKIIQDIDLCENSVQRHIGHANLTFEQLRSLMESLPGKKVGAEDIEKTIKACKPSDQILKLLSLWRIKNGDQDTLKGLMHALKHSKTYHFPKTVTQSLKKTIRFLHSFTMYKLYQKLFLEMIGNQVQSVKISCLSGRLVPRGSHHHHHH.
Host
Nicotiana benthamiana
Theoretical MW (kDa)
45.6
Form
Liquid
Preparation Method
Baculovirus expression system
Purity
> 85% by SDS PAGE
Storage Buffer
PBS pH-7.4 and 10% glycerol.
Storage Instruction
Store at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles.
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Applications
SDS-PAGE
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Gene Info — TNFRSF11B
Entrez GeneID
4982Protein Accession#
O00300Gene Name
TNFRSF11B
Gene Alias
MGC29565, OCIF, OPG, TR1
Gene Description
tumor necrosis factor receptor superfamily, member 11b
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. [provided by RefSeq
Other Designations
osteoclastogenesis inhibitory factor|osteoprotegerin
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Interactome
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Pathway
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Disease
- Acute Disease
- Alveolar Bone Loss
- Alzheimer disease
- Arthritis
- Asthma
- Body Weight
- Bone Diseases
- Brain Ischemia
- Calcinosis
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