LIF (Human) Recombinant Protein
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Specification
Product Description
Human LIF (P15018, 23 a.a. - 202 a.a.) partial-length recombinant protein with His-tag at N-terminal expressed in Escherichia coli.
Sequence
MKHHHHHHASPLPITPVNATCAIRHPCHNNLMNQIRSQLAQLNGSANALFILYYTAQGEPFPNNLDKLCGPNVTDFPPFHANGTEKAKLVELYRIVVYLGTSLGNITRDQKILNPSALSLHSKLNATADILRGLLSNVLCRLCSKYHVGHVDVTYGPDTSGKDVFQKKKLGCQLLGKYKQIIAVLAQAF.
Host
Escherichia coli
Theoretical MW (kDa)
20.9
Form
Lyophilized
Preparation Method
Escherichia coli expression system
Purity
> 95% by SDS PAGE
Storage Buffer
Lyophilized from 20 mM Tris buffer, 20 mM NaCl and 5% w/v trehalose, pH 7.5.
Storage Instruction
Store at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles.
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Applications
SDS-PAGE
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Gene Info — LIF
Entrez GeneID
3976Protein Accession#
P15018Gene Name
LIF
Gene Alias
CDF, DIA, HILDA
Gene Description
leukemia inhibitory factor (cholinergic differentiation factor)
Omim ID
159540Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a pleiotropic cytokine with roles in several different systems. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal-fetal interface. [provided by RefSeq
Other Designations
D factor|cholinergic differentiation factor|differentiation inhibitory activity|differentiation stimulating factor
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