LIF (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human LIF full-length ORF ( NP_002300.1, 1 a.a. - 202 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MKVLAAGVVPLLLVLHWKHGAGSPLPITPVNATCAIRHPCHNNLMNQIRSQLAQLNGSANALFILYYTAQGEPFPNNLDKLCGPNVTDFPPFHANGTEKAKLVELYRIVVYLGTSLGNITRDQKILNPSALSLHSKLNATADILRGLLSNVLCRLCSKYHVGHVDVTYGPDTSGKDVFQKKKLGCQLLGKYKQIIAVLAQAF
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
48.4
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — LIF
Entrez GeneID
3976GeneBank Accession#
NM_002309.2Protein Accession#
NP_002300.1Gene Name
LIF
Gene Alias
CDF, DIA, HILDA
Gene Description
leukemia inhibitory factor (cholinergic differentiation factor)
Omim ID
159540Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a pleiotropic cytokine with roles in several different systems. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal-fetal interface. [provided by RefSeq
Other Designations
D factor|cholinergic differentiation factor|differentiation inhibitory activity|differentiation stimulating factor
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Interactome
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Pathway
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Disease
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