IL17RA (Human) Recombinant protein
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Specification
Product Description
Human IL17RA (Q96F46, 33 a.a. - 320 a.a) partial recombinant protein with hIgG-His tag at C-terminal expressed in Sf9 cells.
Sequence
LRLLDHRALV CSQPGLNCTV KNSTCLDDSW IHPRNLTPSS PKDLQIQLHF AHTQQGDLFP VAHIEWTLQT DASILYLEGA ELSVLQLNTN ERLCVRFEFL SKLRHHHRRW RFTFSHFVVD PDQEYEVTVH HLPKPIPDGD PNHQSKNFLV PDCEHARMKV TTPCMSSGSL WDPNITVETL EAHQLRVSFT LWNESTHYQI LLTSFPHMEN HSCFEHMHHI PAPRPEEFHQ RSNVTLTLRN LKGCCRHQVQ IQPFFSSCLN DCLRHSATVS CPEMPDTPEP IPDYMPLWVE PKSCDKTHTC PPCPAPELLG GPSVFLFPPK PKDTLMISRT PEVTCVVVDV SHEDPEVKFN WYVDGVEVHN AKTKPREEQY NSTYRVVSVL TVLHQDWLNG KEYKCKVSNK ALPAPIEKTI SKAKGQPREP QVYTLPPSRD ELTKNQVSLT CLVKGFYPSD IAVEWESNGQ PENNYKTTPP VLDSDGSFFL YSKLTVDKSR WQQGNVFSCS VMHEALHNHY TQKSLSLSPG KHHHHHH.
Host
insect
Theoretical MW (kDa)
60.4
Form
Liquid
Preparation Method
Insect cell (Sf9) expression system
Purity
> 90% by SDS-PAGE.
Storage Buffer
In PBS, pH 7.4 and 10% glycerol
Storage Instruction
Store at 4°C for 2~4 week. For long term storage store at -20°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Aliquot to avoid repeated freezing and thawing. -
Applications
SDS-PAGE
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Gene Info — IL17RA
Entrez GeneID
23765Protein Accession#
Q96F46Gene Name
IL17RA
Gene Alias
CD217, CDw217, IL-17RA, IL17R, MGC10262, hIL-17R
Gene Description
interleukin 17 receptor A
Omim ID
605461Gene Ontology
HyperlinkGene Summary
Interleukin 17A (IL17A)is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. [provided by RefSeq
Other Designations
interleukin 17A receptor
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Interactome
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Pathway
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Disease
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