IL17R (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human IL17R partial ORF ( NP_055154, 33 a.a. - 132 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
LRLLDHRALVCSQPGLNCTVKNSTCLDDSWIHPRNLTPSSPKDLQIQLHFAHTQQGDLFPVAHIEWTLQTDASILYLEGAELSVLQLNTNERLCVRFEFL
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — IL17RA
Entrez GeneID
23765GeneBank Accession#
NM_014339Protein Accession#
NP_055154Gene Name
IL17RA
Gene Alias
CD217, CDw217, IL-17RA, IL17R, MGC10262, hIL-17R
Gene Description
interleukin 17 receptor A
Omim ID
605461Gene Ontology
HyperlinkGene Summary
Interleukin 17A (IL17A)is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. [provided by RefSeq
Other Designations
interleukin 17A receptor
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Interactome
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Pathway
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Disease
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