MAP2K6 (Human) Recombinant Protein
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Specification
Product Description
Human MAP2K6 (P52564, 1 a.a. - 334 a.a.) full-length recombinant protein with His tag expressed in Baculovirus.
Sequence
MSQSKGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIMELGRGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALFREGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNVLINALGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSAEFVDFTSQCLKKNSKERPTYPELMQHPFFTLHESKGTDVASFVKLILGD
Host
Viruses
Theoretical MW (kDa)
38.3
Form
Liquid
Preparation Method
Baculovirus expression system
Purity
> 90% as analyzed by SDS-PAGE.
Endotoxin Level
< 1 EU/ug of protein by the LAL method.
Quality Control Testing
SDS-PAGE Stained with Coomassie Blue.
SDS-PAGE analysis of MAP2K6 (Human) Recombinant Protein.
Recommend Usage
SDS-PAGE
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 ( 20% glycerol)
Storage Instruction
Store at 4°C for 1 week. For long term storage store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
SDS-PAGE
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Gene Info — MAP2K6
Entrez GeneID
5608Protein Accession#
P52564Gene Name
MAP2K6
Gene Alias
MAPKK6, MEK6, MKK6, PRKMK6, SAPKK3
Gene Description
mitogen-activated protein kinase kinase 6
Omim ID
601254Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis. [provided by RefSeq
Other Designations
protein kinase, mitogen-activated, kinase 6 (MAP kinase kinase 6)
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Interactome
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Disease
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