MAP2K6 (Human) Recombinant Protein
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SDS-PAGE analysis of MAP2K6 (Human) Recombinant Protein
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Specification
Product Description
Human MAP2K6 (NP_002749, 53 a.a. - 314 a.a ) partial recombinant protein with His tag expressed in Escherichia coli.
Sequence
MGSSHHHHHHSSGLVPRGSHMLEPIMELGRGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALFREGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNVLINALGQVKMCDFGISGYLVDEVAKEIDAGCKPYMAPERINPELNQKGYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSAEFVDFTSQCLKKNSKERPTYPELMQHPFF
Host
Escherichia coli
Theoretical MW (kDa)
32
Form
Liquid
Preparation Method
Escherichia coli expression system
Purity
> 85% by SDS-PAGE
Quality Control Testing
3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.
SDS-PAGE analysis of MAP2K6 (Human) Recombinant Protein
Recommend Usage
SDS-PAGE
Denatured
The optimal working dilution should be determined by the end user.Storage Buffer
In 20mM Tris-HCl buffer, pH8.0 (10% glycerol).
Storage Instruction
Store at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
SDS-PAGE
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Gene Info — MAP2K6
Entrez GeneID
5608Protein Accession#
P52564Gene Name
MAP2K6
Gene Alias
MAPKK6, MEK6, MKK6, PRKMK6, SAPKK3
Gene Description
mitogen-activated protein kinase kinase 6
Omim ID
601254Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis. [provided by RefSeq
Other Designations
protein kinase, mitogen-activated, kinase 6 (MAP kinase kinase 6)
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Interactome
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Pathway
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Disease
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