VCAM1 monoclonal antibody, clone STA (APC)
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Specification
Product Description
Mouse monoclonal antibody raised against native VCAM1.
Immunogen
Native purified VCAM1 from human DS6 T cell line.
Host
Mouse
Theoretical MW (kDa)
100-110
Reactivity
Human
Specificity
The mouse monoclonal antibody STA recognizes VCAM1 (CD106 antigen), a 100-110 kDa type I membrane protein of the immunoglobulin superfamily, a crucial mediator of leukocyte adhesion, and a costimulation molecule.
Form
Liquid
Conjugation
APC
Purification
Size-exclusion chromatography purification
Isotype
IgG1
Recommend Usage
Flow Cytometry (10 uL reagent/100 uL of whole blood or 106 cells)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (0.02% BSA, 0.09% sodium azide)
Storage Instruction
Store in the dark at 4°C. Avoid prolonged exposure to light. Do not freeze.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Flow Cytometry
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Gene Info — VCAM1
Entrez GeneID
7412Gene Name
VCAM1
Gene Alias
CD106, DKFZp779G2333, INCAM-100, MGC99561
Gene Description
vascular cell adhesion molecule 1
Omim ID
192225Gene Ontology
HyperlinkGene Summary
This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Two alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq
Other Designations
CD106 antigen|OTTHUMP00000012650|OTTHUMP00000012651
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Interactome
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