CD1A monoclonal antibody, clone RM393
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human CD1A.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to N-terminus of human CD1A.
Reactivity
Human
Specificity
This antibody reacts to human T-cell surface glycoprotein CD1A.
Form
Liquid
Purification
Protein A purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:100-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (50% glycerol, 1% BSA, 0.09% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human skin with CD1A monoclonal antibody, clone RM393 (Cat # MAB23173) at a 1:100 dilution.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human thymus with CD1A monoclonal antibody, clone RM393 (Cat # MAB23173) at a 1:100 dilution. -
Gene Info — CD1A
Entrez GeneID
909Gene Name
CD1A
Gene Alias
CD1, FCB6, HTA1, R4, T6
Gene Description
CD1a molecule
Omim ID
188370Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternatively spliced transcript variants have been observed, but their biological validity has not been determined. [provided by RefSeq
Other Designations
CD1A antigen|CD1A antigen, a polypeptide|OTTHUMP00000018907|T-cell surface antigen T6/Leu-6|T-cell surface glycoprotein CD1a|cluster of differentiation 1 A|cortical thymocyte antigen CD1A|differentiation antigen CD1-alpha-3|epidermal dendritic cell marker
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Interactome
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Disease
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