CLEC7A monoclonal antibody, clone 4G2G6
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: CLEC7A-hIgGFc transfected HEK293 cell lysates with CLEC7A monoclonal antibody, clone 4G2G6 (Cat # MAB21447).
Enzyme-linked Immunoabsorbent Assay
ELISA analysis with CLEC7A monoclonal antibody, clone 4G2G6 (Cat # MAB21447).
Flow Cytometry
Flow cytometric analysis of HL-60 cells with CLEC7A monoclonal antibody, clone 4G2G6 (Cat # MAB21447) (Green). Red: Negative Control.
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human CLEC7A.
Immunogen
Recombinant protein corresponding to amino acids 66-247 of human CLEC7A.
Host
Mouse
Theoretical MW (kDa)
27.6
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Flow Cytometry (1:200-1:400)
Immunocytochemistry (1:200-1:1000)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: CLEC7A-hIgGFc transfected HEK293 cell lysates with CLEC7A monoclonal antibody, clone 4G2G6 (Cat # MAB21447).Immunocytochemistry
Enzyme-linked Immunoabsorbent Assay
ELISA analysis with CLEC7A monoclonal antibody, clone 4G2G6 (Cat # MAB21447).Flow Cytometry
Flow cytometric analysis of HL-60 cells with CLEC7A monoclonal antibody, clone 4G2G6 (Cat # MAB21447) (Green). Red: Negative Control. -
Gene Info — CLEC7A
Entrez GeneID
64581Protein Accession#
Q9BXN2Gene Name
CLEC7A
Gene Alias
BGR, CLECSF12, DECTIN1
Gene Description
C-type lectin domain family 7, member A
Omim ID
606264Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq
Other Designations
C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 12|beta-glucan receptor|dectin-1|dendritic cell-associated C-type lectin 1|dendritic cell-associated C-type lectin-1|lectin-like receptor 1
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Interactome
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Disease
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